Abstract
Tembusu virus (TMUV) infection in ducks, geese and house sparrows was reported in China. To confirm the emergence of TMUV in humans, we investigated TMUV as a possible infection in duck industry workers in Shandong, China. Of 132 serum samples tested, 95 (71.9%) had TMUV antibodies. In oral swabs detection, 63 (47.7%) samples were positive for TMUV RNA. Nucleotide sequences of 277 bp coding the partial NS3 protein showed more than 99.5% identity with other duck TMUV strains, which can cause severe egg drop in ducks. These findings contribute to the realization that TMUV may be overlooked as a zoonotic transmission in China.
© 2013 Blackwell Verlag GmbH.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antibodies, Neutralizing / blood
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Antibodies, Viral / blood*
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China
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Ducks / virology
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Enzyme-Linked Immunosorbent Assay
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Evolution, Molecular
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Flavivirus / genetics
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Flavivirus / isolation & purification
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Flavivirus / pathogenicity*
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Flavivirus Infections / diagnosis*
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Humans
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Mouth Mucosa / virology*
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Occupational Diseases / diagnosis
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Phylogeny
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Polymerase Chain Reaction
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Poultry Diseases / diagnosis
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Poultry Diseases / virology
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RNA Helicases / genetics
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RNA, Messenger / genetics
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RNA, Viral / blood
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RNA, Viral / genetics
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Reverse Transcriptase Polymerase Chain Reaction
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Serine Endopeptidases / genetics
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Viral Load
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Viral Nonstructural Proteins / genetics*
Substances
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Antibodies, Neutralizing
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Antibodies, Viral
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NS3 protein, flavivirus
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RNA, Messenger
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RNA, Viral
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Viral Nonstructural Proteins
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Serine Endopeptidases
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RNA Helicases